2005 PPBT Summer Seminar Syllabus

Note: Some resources are restricted to UC access only.

Week One

July 18

Program Overview
Peter Cowhey
Sam Bozzette

Abbott, Alison. 2005. "What’s in the Medicine Cabinet?" Nature 435:407–409. Available at http://www.nature.com/nature/journal/v435/n7041/pdf/435407a.pdf

Committee on Defense Intelligence Agency Technology Forecasts and Reviews. 2005. Avoiding Surprise in an Era of Global Technology. National Academies Press. 138 pages.

Fouchier, Ron et al. 2005. "Global Task Force for Influenza. " Nature 435: 419–20. Available at http://www.nature.com/news/2005/050523/pf/435419a_pf.html

Garrett, Laurie. 2005. "The Next Pandemic?" Foreign Affairs 84,4 (July/August): 3-23. Available online at EBSCO.

Konkel, Todd. 2005. "Container Security: Preventing a Nuclear Catastrophe." International Policy Solutions 2 (1). 23 pages.

Long, Jeremy. 2005. "Stopping Terrorist Operatives: A Supply-side Approach." International Policy Solutions 2 (1). 27 pages.

Osterholm, Michael T. 2005. " Preparing for the Next Pandemic." Foreign Affairs 84, 4 (July/August). 24-37. Available at EBSCO.

Introduction to Biothreats
Sam Bozzette

Enserink, Martin. 2005. "Crisis of Confidence Hampers Marburg Control in Angola." Science, April 22 . Available at http://www.sciencemag.org/cgi/content/full/308/5721/489

Segal, Lawrence. 2002. "Unit 731: Medical Madness in the 'Other' Holocaust." Can. J. Diagnosis (March) . Available at http://www.stacommunications.com/pdf/marpdf/DXMAR02/055MedofHist.pdf

Wu, Tien-wei . "'A Preliminary Review of Studies of Japanese Biological Warfare and Unit 731 in the United States." Review of Japanese Biological Warfare and Unit 731. Available at http://www.centurychina.com/wiihist/germwar/731rev.htm.

Butler, Declan. 2005. “The Flu Pandemic: Were We Ready?” Nature, May 26, 400–402. Available at http://www.nature.com/nature/journal/v435/n7041/full/435400a.html

Epidemiology and Emerging Infections
Michele Ginsberg

Website resources:
Microbial Threats to Health - www.iom.edu
Emerging Infectious Diseases Journal - www.cdc.gov
PRO-MED - www.promed.org
World Health Organization - www.who.int/en/

Introduction to Biothreats II: Why Are We Worried?
Sam Bozzette

July 19

Bioscience 101
Kit Pogliano

Viruses and Vaccination
Samuel Stanley

July 20

History and Treatment of Infectious Diseases
Josh Fierer

History and Treatment of Infectious Diseases: Vectors
Sam Bozzette

July 21

Public Health Response
Nicole Lurie

Bioweapons: Weaponization and Related Issues
Dean Wilkening

July 22

Surveillance and Remote Sensing
Frank Garland

Altman, Sidney et al. 2005. “An Open Letter to Elias Zerhouni.”Science 307:1409–10. Available at http://www.sciencemag.org/cgi/content/short/307/5714/1409c

Bravata, Dena M. et al. 2004. "Systematic Review: Surveillance Systems for Early Detection of Bioterrorism-Related Diseases." Annals of Internal Medicine 140:910–22. Available at http://www.annals.org/cgi/reprint/140/11/910.pdf

Buehler, James W. et al. 2003. "Syndromic Surveillance and Bioterrorism-related Epidemics." Emerging Infectious Diseases 9 (10): 1197–1204. Available at http://www.cdc.gov/ncidod/EID/vol9no10/03-0231.htm

Fauci, A.S., and E. A. Zerhouni. 2005. "NIH Response to Open Letter." Science 308: 49. Available at http://www.sciencemag.org/cgi/content/full/308/5718/49b

RAND Corporation. 2004. "Syndromic Surveillance: An Effective Tool for Detecting Bioterrorism?" RAND Research Highlights. Available at http://www.rand.org/publications/RB/RB9042/RB9042.pdf

Biological Arms Control and Verification
Raymond Zilinskas

Ad Hoc Group of Governmental Experts to Identify and Examine Potential Verification Measures From a Scientific and Technical Standpoint. September 23, 1993. 44 pages .

Zilinskas, Raymond A. 1995. "Symposium: Biological Weapons Inspection." Politics and the Life Sciences (August): 229–62.

Week Two

July 25

History of Bioterrorism
David Rapoport

The Political Economy of Terrorism
Barbara Walter

July 26

Introduction to Policy Analysis
Sam Bozzette
Peter Cowhey

Policy Implementation
Jessica Wallack

Gupta, Dipak K. 2001. Analyzing Public Policy: Concepts, Tools, and Techniques, 46–69.Washington, D.C.: Congressional Quarterly.

Leitenberg, M. and G. Smith. June 2005. "Got Toxic Milk? A Rejoinder." Federation of American Scientists. Available at http://www.fas.org/sgp/eprint/milk.html

Wein, Lawrence M., and Yifan Liu. 2005. "Analyzing a Bioterror Attack on the Food Supply: The Case of Botulinum Toxin in Milk." Proceedings of the National Academy of Sciences. 12 July. 6 pages. Available at www.pnas.org.

Wein, Lawrence M. 2005. "Got Toxic Milk?" New York Times, May 30. Editorial. Available at http://www.honksandsirens.com/cached/milk.html

July 27

Economics of Pharmaceutical and Biotech Industry Innovations and Policy Options for Drug/Vaccine Development
Darren Filson

Government and Regulatory Perspectives
Michael Friedman

July 28

National Security Decision Making
Michael Nacht
Richard Feinberg

Friedman, Benjamin. 2005. "Homeland Security." Foreign Policy 149 (July/August): 22–28.

The Challenge of Establishing Cross-Border Policies in Developing Countries
Clark Gibson

July 29

Agroterrorism Agricultural Threats
Mark Wheelis

Wheelis, Mark, Rocco Casagrande, and Laurence V. Madden. 2002. "Biological Attack on Agriculture: Low-Tech, High-Impact Bioterrorism." BioScience 52 (7): 569–76. 8 pages.

International Efforts to Counter Bioterrorism and Emergent Biological Threats
Mark Smolinski

Smolinski, Mark S., Margaret A. Hamburg, and Joshua Lederberg, eds. 2003. Microbial Threats to Health: Emergence, Detection, and Response. Washington, D.C.: National Academies Press. Available at http://books.nap.edu/books/030908864X/html/index.html. Accessed 6 October 2004.

Week Three

August 1

Bioshield II and Counter-Bioterrorism Legislation
Chuck Ludlam

Lieberman, Joseph. 2004. "Creating Biodefense Industry: Bioshield II." Testimony by Senator Joseph Lieberman Before the Senate Judiciary and Senate HELP Committees. 52 pages. Available at http://lieberman.senate.gov/.

Bioshield II, S. 975. 25 pages.
Available at http://thomas.loc.gov/.

August 2

Case Study: Bay Area Emergency Planning
Michael Kleeman
Gregg O’Ryon

Case Study: Bay Area Emergency Planning
(Chain of Command)
Michael Kleeman
Gregg O’Ryon

August 3

Legal Issues
Margaret McKeown
David Law

Public Health Responses During the SARS Outbreak in SE Asia (Videoconference)
Tan Chorh Chuan

Centers for Disease Control and Prevention. 2003. "Severe Acute Respiratory Syndrome - Singapore, 2003," MMWR Weekly, May 9, 405–11.

Gopalakrishna, Gowri, Phillip Choo, Yee Sin Leo, et al. "SARS Transmission and Hospital Containment." 6 pages.

King, Arelene, C. C. Tan, T. Tsang, and Margaret Chan. 2005. “Public Health Response: A View from Three Cities.” In Severe Acute Respiratory Syndrome: A Clinical Guide, edited by Malik Peiris, Larry Anderson, Albert DME Osterhaus, et al. London: Blackwell.

Lipsitch, Marc, et al. 2003. "Transmission Dynamics and Control of Severe Acute Respiratory Syndrome." Science, 20 June, 1966–70.

Skowronski, Danuta M., Caroline Astell, Robert C. Brunham, et al. 2005. "Severe Acute Respiratory Syndrome (SARS): A Year in Review." Annual Review of Medicine 56:357–83.

August 4

Case Study: Smallpox Vaccine Development
Sam Bozzette

Agricultural Threat Case Study
Jerry Gillespie

August 5

Communications and Media
John Cohen
Bree Walker

Closing Speaker
Julie Gerberding